Değerli Dostlar,
Haseki Eğitim ve Araştırma Hastanesinde Kliniğimizde (4.iç hastalıkları kliniği) 10 yıl önce başlayan ve 2009 yılında uluslararası dergilerde sonuçları yayınlanan ''Carotid intima-media thickness (IMT) is a key predictor of cardiovascular mortality and morbidity in patients with type 2 diabetes'' adlı bilimsel çalışma kliniğimiz baş asistanı Dr H. Esra Ataoğlu tarafından uluslararası tıp kongrelerinde sunuldu. Reuters ajansı bu başarılı çalışmayı tüm dünyaya servis etti ve başasistanımızla bu konuda röpörtaj yaparak konuyu dünya basın kuruluşlarına iletti.
Dr.Mustafa Yenigün.
Haseki Eğitim ve Araştırma Hastanesi Klinik şefi.
Reuters Health Stories
Epidemiology
Carotid thickness testing improves cardiovascular risk assessment in diabetics
by Will Boggs, MD
Last Updated: 2009-10-16 17:36:26 -0400 (Reuters Health)
NEW YORK (Reuters Health) - Carotid intima-media thickness (IMT) is a key predictor of cardiovascular mortality and morbidity in patients with type 2 diabetes, researchers from Turkey report in the September Journal of Diabetes. "Each patient must be thoroughly examined for cardiovascular risk assessment," Dr. Hayriye Esra Ataoglu from Haseki Training and Research Hospital, Fatih, told Reuters Health. "Carotid IMT and microalbuminuria must be included in the conventional risk assessment."
Dr. Ataoglu and colleagues assessed the changes in coronary risk prediction conferred by carotid IMT, Framingham risk score, and other clinical parameters, over a period of 10 years in 102 patients with type 2 diabetes who did not have cardiovascular disease. Carotid artery IMT of 0.9 mm or more, urinary albumin excretion of 30 mg/day or more, and Framingham risk score of 20 or more together were associated with an 8.8-fold increased likelihood of cardiovascular primary endpoints, the authors report. In a logistic regression model, backward stepwise analysis identified male gender, diastolic blood pressure, and carotid IMT as the most important factors for predicting cardiovascular endpoints. Urinary albumin excretion, carotid IMT, and Framingham 10-year risk score were the most important risk factors in an alternative regression model designed to evaluate their effects on cardiovascular endpoints.
"Carotid IMT must be included in the risk assessment of patients with diabetes," Dr. Ataoglu said. "Carotid IMT should be assessed in these patients at first evaluation. A five-year follow-up period for repeating this evaluation seems reasonable." "We are working on the relationship of carotid IMT with complications of diabetics," Dr. Ataoglu added. "There is another ongoing study in our clinic about ankle-brachial index and carotid IMT in diabetic patients."
J Diabetes 2009;1:188-193.